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RAGE inhibition blunts insulin-induced oncogenic signals in breast cancer

The receptor for advanced glycation end products (RAGE) is implicated in diabetes and obesity complications, as well as in breast cancer (BC). Herein, we evaluated whether RAGE contributes to the oncogenic actions of Insulin, which plays a key role in BC progression particularly in obese and diabeti...

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Detalles Bibliográficos
Autores principales: Muoio, M. G., Pellegrino, M., Rapicavoli, V., Talia, M., Scavo, G., Sergi, V., Vella, V., Pettinato, S., Galasso, M. G., Lappano, R., Scordamaglia, D., Cirillo, F., Pulvirenti, A., Rigiracciolo, D. C., Maggiolini, M., Belfiore, A., De Francesco, E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351154/
https://www.ncbi.nlm.nih.gov/pubmed/37461077
http://dx.doi.org/10.1186/s13058-023-01686-5