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Comprehensive analysis of neoantigens derived from structural variation across whole genomes from 2528 tumors
BACKGROUND: Neoantigens are critical for anti-tumor immunity and have been long-envisioned as promising therapeutic targets. However, current neoantigen analyses mostly focus on single nucleotide variations (SNVs) and indel mutations and seldom consider structural variations (SVs) that are also prev...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351168/ https://www.ncbi.nlm.nih.gov/pubmed/37461029 http://dx.doi.org/10.1186/s13059-023-03005-9 |