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Sensitive inference of alignment-safe intervals from biodiverse protein sequence clusters using EMERALD

Sequence alignments are the foundations of life science research, but most innovation so far focuses on optimal alignments, while information derived from suboptimal solutions is ignored. We argue that one optimal alignment per pairwise sequence comparison is a reasonable approximation when dealing...

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Detalles Bibliográficos
Autores principales: Grigorjew, Andreas, Gynter, Artur, Dias, Fernando H. C., Buchfink, Benjamin, Drost, Hajk-Georg, Tomescu, Alexandru I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351170/
https://www.ncbi.nlm.nih.gov/pubmed/37461051
http://dx.doi.org/10.1186/s13059-023-03008-6