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Genomic analyses of germline and somatic variation in high-grade serous ovarian cancer

BACKGROUND: High-grade serous ovarian cancers (HGSCs) display a high degree of complex genetic alterations. In this study, we identified germline and somatic genetic alterations in HGSC and their association with relapse-free and overall survival. Using a targeted capture of 557 genes involved in DN...

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Detalles Bibliográficos
Autores principales: Adamson, A. W., Ding, Y. C., Steele, L., Leong, L. A., Morgan, R., Wakabayashi, M. T., Han, E. S., Dellinger, T. H., Lin, P. S., Hakim, A. A., Wilczynski, S., Warden, C. D., Tao, S., Bedell, V., Cristea, M. C., Neuhausen, S. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351177/
https://www.ncbi.nlm.nih.gov/pubmed/37460928
http://dx.doi.org/10.1186/s13048-023-01234-x