Cargando…

IL-1RA promotes oral squamous cell carcinoma malignancy through mitochondrial metabolism-mediated EGFR/JNK/SOX2 pathway

BACKGROUND: Interleukin-1 receptor antagonist (IL-1RA), a member of the IL-1 family, has diverse roles in cancer development. However, the role of IL-1RA in oral squamous cell carcinoma (OSCC), in particular the underlying mechanisms, remains to be elucidated. METHODS: Tumor tissues from OSCC patien...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Shyng-Shiou F., Wang, Yun-Ming, Chan, Leong-Perng, Hung, Amos C., Nguyen, Hieu D. H., Chen, Yuk-Kwan, Hu, Stephen Chu‐Sung, Lo, Steven, Wang, Yen-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351194/
https://www.ncbi.nlm.nih.gov/pubmed/37461111
http://dx.doi.org/10.1186/s12967-023-04343-9