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IL-1RA promotes oral squamous cell carcinoma malignancy through mitochondrial metabolism-mediated EGFR/JNK/SOX2 pathway
BACKGROUND: Interleukin-1 receptor antagonist (IL-1RA), a member of the IL-1 family, has diverse roles in cancer development. However, the role of IL-1RA in oral squamous cell carcinoma (OSCC), in particular the underlying mechanisms, remains to be elucidated. METHODS: Tumor tissues from OSCC patien...
Autores principales: | Yuan, Shyng-Shiou F., Wang, Yun-Ming, Chan, Leong-Perng, Hung, Amos C., Nguyen, Hieu D. H., Chen, Yuk-Kwan, Hu, Stephen Chu‐Sung, Lo, Steven, Wang, Yen-Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351194/ https://www.ncbi.nlm.nih.gov/pubmed/37461111 http://dx.doi.org/10.1186/s12967-023-04343-9 |
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