Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes

BACKGROUND AND OBJECTIVES: Injured pericytes in the neurovascular unit release platelet-derived growth factor β (PDGFRβ) into the CSF. However, it is not clear how pericyte injury contributes to Alzheimer disease (AD)–related changes and blood-brain barrier (BBB) damage. We aimed to test whether CSF...

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Detalles Bibliográficos
Autores principales: Cicognola, Claudia, Mattsson-Carlgren, Niklas, van Westen, Danielle, Zetterberg, Henrik, Blennow, Kaj, Palmqvist, Sebastian, Ahmadi, Khazar, Strandberg, Olof, Stomrud, Erik, Janelidze, Shorena, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351311/
https://www.ncbi.nlm.nih.gov/pubmed/37137722
http://dx.doi.org/10.1212/WNL.0000000000207358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351311/
https://www.ncbi.nlm.nih.gov/pubmed/37137722
http://dx.doi.org/10.1212/WNL.0000000000207358

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