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Design, synthesis and evaluation of a myricetin and nobiletin hybrid compound for alleviating hyperuricemia based on metabolomics and gut microbiota

Hyperuricemia (HUA) is the fourth most common basic metabolic disease that can cause damage to multiple organs throughout the body. In this study, a hybrid compound consisting of myricetin and nobiletin was synthesized and its biological activity was evaluated. We named the hybrid compound MNH, and...

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Detalles Bibliográficos
Autores principales: Li, Yan, Pu, Liu-Yang, Li, Yayun, Zhu, Guanbao, Wu, Zhengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351364/
https://www.ncbi.nlm.nih.gov/pubmed/37465570
http://dx.doi.org/10.1039/d3ra03188h