Siglec-15 Promotes Evasion of Adaptive Immunity in B-cell Acute Lymphoblastic Leukemia

Siglec-15 (Sig15) has been implicated as an immune checkpoint expressed in solid tumor-infiltrating macrophages and is being targeted in clinical trials with mAbs to normalize the tumor immune microenvironment and stimulate antitumor immunity. However, the role of Sig15 in hematologic malignancies r...

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Detalles Bibliográficos
Autores principales: Pillsbury, Claire E., Dougan, Jodi, Rabe, Jennifer L., Fonseca, Jairo A., Zhou, Chengjing, Evans, Alyssa N., Abukharma, Hasan, Ichoku, Ona, Gonzalez-Flamenco, Gloria, Park, Sunita I., Aljudi, Ahmed, DeRyckere, Deborah, Castellino, Sharon M., Rafiq, Sarwish, Langermann, Solomon, Liu, Linda N., Henry, Curtis J., Porter, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351425/
https://www.ncbi.nlm.nih.gov/pubmed/37465593
http://dx.doi.org/10.1158/2767-9764.CRC-23-0056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351425/
https://www.ncbi.nlm.nih.gov/pubmed/37465593
http://dx.doi.org/10.1158/2767-9764.CRC-23-0056

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