Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction

Macroautophagy/autophagy is a catabolic process by which cytosolic content is engulfed, degraded and recycled. It has been implicated as a critical pathway in advanced stages of cancer, as it maintains tumor cell homeostasis and continuous growth by nourishing hypoxic or nutrient-starved tumors. Aut...

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Detalles Bibliográficos
Autores principales: Nuta, Gal Chaim, Gilad, Yuval, Goldberg, Nadav, Meril, Sara, Bahlsen, Marcela, Carvalho, Silvia, Kozer, Noga, Barr, Haim, Fridmann Sirkis, Yael, Hercík, Kamil, Břehová, Petra, Nencka, Radim, Bialik, Shani, Eisenstein, Miriam, Kimchi, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper - translational
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351452/
https://www.ncbi.nlm.nih.gov/pubmed/37184247
http://dx.doi.org/10.1080/15548627.2023.2178159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351452/
https://www.ncbi.nlm.nih.gov/pubmed/37184247
http://dx.doi.org/10.1080/15548627.2023.2178159

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