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Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction
Macroautophagy/autophagy is a catabolic process by which cytosolic content is engulfed, degraded and recycled. It has been implicated as a critical pathway in advanced stages of cancer, as it maintains tumor cell homeostasis and continuous growth by nourishing hypoxic or nutrient-starved tumors. Aut...
Autores principales: | Nuta, Gal Chaim, Gilad, Yuval, Goldberg, Nadav, Meril, Sara, Bahlsen, Marcela, Carvalho, Silvia, Kozer, Noga, Barr, Haim, Fridmann Sirkis, Yael, Hercík, Kamil, Břehová, Petra, Nencka, Radim, Bialik, Shani, Eisenstein, Miriam, Kimchi, Adi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351452/ https://www.ncbi.nlm.nih.gov/pubmed/37184247 http://dx.doi.org/10.1080/15548627.2023.2178159 |
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