A distinct variant of the SzM protein of Streptococcus equi subsp. zooepidemicus recruits C1q independent of IgG binding and inhibits activation of the classical complement pathway

Streptococcus equi subsp. zooepidemicus (SEZ) is a major equine pathogen that causes pneumonia, abortion, and polyarthritis. It can also cause invasive infections in humans. SEZ expresses the M-like protein SzM, which recruits host proteins such as fibrinogen to the bacterial surface. Equine SEZ str...

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Detalles Bibliográficos
Autores principales: Bergmann, René, Schroedl, Wieland, Müller, Uwe, Baums, Christoph Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351459/
https://www.ncbi.nlm.nih.gov/pubmed/37450582
http://dx.doi.org/10.1080/21505594.2023.2235461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351459/
https://www.ncbi.nlm.nih.gov/pubmed/37450582
http://dx.doi.org/10.1080/21505594.2023.2235461

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