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Neurofilament light chain levels in cerebrospinal fluid as a sensitive biomarker for cerebral adrenoleukodystrophy

OBJECTIVE: Adrenoleukodystrophy (ALD) has a poor prognosis when it progresses to the cerebral form (CALD). The aim of this study is to investigate whether cerebrospinal fluid (CSF) neurofilament light chain (cNfL) is a sensitive biomarker for detecting CALD and assessing response to hematopoietic st...

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Detalles Bibliográficos
Autores principales: Kakumoto, Toshiyuki, Matsukawa, Takashi, Ishiura, Hiroyuki, Mori, Harushi, Tsuji, Shoji, Toda, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351652/
https://www.ncbi.nlm.nih.gov/pubmed/37259474
http://dx.doi.org/10.1002/acn3.51818