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Cis-regulatory Landscape Size, Constraint, and Tissue Specificity Associate with Gene Function and Expression
Multiple distal cis-regulatory elements (CREs) often cooperate to regulate gene expression, and the presence of multiple CREs for a gene has been proposed to provide redundancy and robustness to variation. However, we do not understand how attributes of a gene's distal CRE landscape—the CREs th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351668/ https://www.ncbi.nlm.nih.gov/pubmed/37410590 http://dx.doi.org/10.1093/gbe/evad126 |