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Effects of pH alteration on respiratory syncytial virus in human airway epithelial cells

BACKGROUND: Respiratory syncytial virus (RSV) is a leading cause of respiratory distress and hospitalisation in the paediatric population. Low airway surface pH impairs antimicrobial host defence and worsens airway inflammation. Inhaled Optate safely raises airway surface pH in humans and raises int...

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Detalles Bibliográficos
Autores principales: Saunders, Jessica L., Daniels, Ivana A., Edwards, Taiya L., Relich, Ryan F., Zhao, Yi, Smith, Laura A., Gaston, Benjamin M., Davis, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351676/
https://www.ncbi.nlm.nih.gov/pubmed/37465558
http://dx.doi.org/10.1183/23120541.00404-2022