Complex subsets but redundant clonality after B cells egress from spontaneous germinal centers

Affinity matured self-reactive antibodies are found in autoimmune diseases like systemic lupus erythematous. Here, we used fate-mapping reporter mice and single-cell transcriptomics coupled to antibody repertoire analysis to characterize the post-germinal center (GC) B cell compartment in a new mous...

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Detalles Bibliográficos
Autores principales: Castrillon, Carlos, Simoni, Lea, van den Broek, Theo, van der Poel, Cees, Akama-Garren, Elliot H, Ma, Minghe, Carroll, Michael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351918/
https://www.ncbi.nlm.nih.gov/pubmed/37341394
http://dx.doi.org/10.7554/eLife.81012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351918/
https://www.ncbi.nlm.nih.gov/pubmed/37341394
http://dx.doi.org/10.7554/eLife.81012

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