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Feature weighted models to address lineage dependency in drug-resistance prediction from Mycobacterium tuberculosis genome sequences

MOTIVATION: Tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex (MTBC), which has a strain- or lineage-based clonal population structure. The evolution of drug-resistance in the MTBC poses a threat to successful treatment and eradication of TB. Machine learning approache...

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Detalles Bibliográficos
Autores principales: Billows, Nina, Phelan, Jody E, Xia, Dong, Peng, Yonghong, Clark, Taane G, Chang, Yu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351970/
https://www.ncbi.nlm.nih.gov/pubmed/37428143
http://dx.doi.org/10.1093/bioinformatics/btad428