Structural and functional understanding of disease-associated mutations in V-ATPase subunit a1 and other isoforms

The vacuolar-type ATPase (V-ATPase) is a multisubunit protein composed of the cytosolic adenosine triphosphate (ATP) hydrolysis catalyzing V(1) complex, and the integral membrane complex, V(o), responsible for proton translocation. The largest subunit of the V(o) complex, subunit a, enables proton t...

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Detalles Bibliográficos
Autores principales: Indrawinata, Karen, Argiropoulos, Peter, Sugita, Shuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352029/
https://www.ncbi.nlm.nih.gov/pubmed/37465367
http://dx.doi.org/10.3389/fnmol.2023.1135015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352029/
https://www.ncbi.nlm.nih.gov/pubmed/37465367
http://dx.doi.org/10.3389/fnmol.2023.1135015

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