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Structural and functional understanding of disease-associated mutations in V-ATPase subunit a1 and other isoforms
The vacuolar-type ATPase (V-ATPase) is a multisubunit protein composed of the cytosolic adenosine triphosphate (ATP) hydrolysis catalyzing V(1) complex, and the integral membrane complex, V(o), responsible for proton translocation. The largest subunit of the V(o) complex, subunit a, enables proton t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352029/ https://www.ncbi.nlm.nih.gov/pubmed/37465367 http://dx.doi.org/10.3389/fnmol.2023.1135015 |