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The current state and future of T-cell exhaustion research

‘Exhaustion’ is a term used to describe a state of native and redirected T-cell hypo-responsiveness resulting from persistent antigen exposure during chronic viral infections or cancer. Although a well-established phenotype across mice and humans, exhaustion at the molecular level remains poorly def...

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Detalles Bibliográficos
Autores principales: Jenkins, Edward, Whitehead, Toby, Fellermeyer, Martin, Davis, Simon J, Sharma, Sumana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352049/
https://www.ncbi.nlm.nih.gov/pubmed/37554723
http://dx.doi.org/10.1093/oxfimm/iqad006