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The current state and future of T-cell exhaustion research
‘Exhaustion’ is a term used to describe a state of native and redirected T-cell hypo-responsiveness resulting from persistent antigen exposure during chronic viral infections or cancer. Although a well-established phenotype across mice and humans, exhaustion at the molecular level remains poorly def...
Autores principales: | Jenkins, Edward, Whitehead, Toby, Fellermeyer, Martin, Davis, Simon J, Sharma, Sumana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352049/ https://www.ncbi.nlm.nih.gov/pubmed/37554723 http://dx.doi.org/10.1093/oxfimm/iqad006 |
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