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OCE-205, a Selective V1a Partial Agonist, Reduces Portal Pressure in Rat Models of Portal Hypertension

PURPOSE: Management of decompensated cirrhosis may include the use of vasoconstrictors that can lead to serious adverse events. OCE-205 was designed as a highly selective V1a receptor partial agonist, intended to have a wider therapeutic window than full vasopressin agonists. METHODS: We aimed to ch...

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Detalles Bibliográficos
Autores principales: Bukofzer, Stan, Harris, Geoffrey, Song, Susan, Cable, Edward E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352125/
https://www.ncbi.nlm.nih.gov/pubmed/37469992
http://dx.doi.org/10.2147/JEP.S416673