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The Mediator complex regulates enhancer-promoter interactions

Enhancer-mediated gene activation generally requires physical proximity between enhancers and their target gene promoters. However, the molecular mechanisms by which interactions between enhancers and promoters are formed are not well understood. Here, we investigate the function of the Mediator com...

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Detalles Bibliográficos
Autores principales: Ramasamy, Shyam, Aljahani, Abrar, Karpinska, Magdalena A., Cao, T. B. Ngoc, Velychko, Taras, Cruz, J. Neos, Lidschreiber, Michael, Oudelaar, A. Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352134/
https://www.ncbi.nlm.nih.gov/pubmed/37430065
http://dx.doi.org/10.1038/s41594-023-01027-2