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The Mediator complex regulates enhancer-promoter interactions
Enhancer-mediated gene activation generally requires physical proximity between enhancers and their target gene promoters. However, the molecular mechanisms by which interactions between enhancers and promoters are formed are not well understood. Here, we investigate the function of the Mediator com...
Autores principales: | Ramasamy, Shyam, Aljahani, Abrar, Karpinska, Magdalena A., Cao, T. B. Ngoc, Velychko, Taras, Cruz, J. Neos, Lidschreiber, Michael, Oudelaar, A. Marieke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352134/ https://www.ncbi.nlm.nih.gov/pubmed/37430065 http://dx.doi.org/10.1038/s41594-023-01027-2 |
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