H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function

Mammalian genomes harbor abundant transposable elements (TEs) and their remnants, with numerous epigenetic repression mechanisms enacted to silence TE transcription. However, TEs are upregulated during early development, neuronal lineage, and cancers, although the epigenetic factors contributing to...

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Detalles Bibliográficos
Autores principales: Pal, Debosree, Patel, Manthan, Boulet, Fanny, Sundarraj, Jayakumar, Grant, Olivia A., Branco, Miguel R., Basu, Srinjan, Santos, Silvia D. M., Zabet, Nicolae Radu, Scaffidi, Paola, Pradeepa, Madapura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352135/
https://www.ncbi.nlm.nih.gov/pubmed/37308596
http://dx.doi.org/10.1038/s41594-023-01016-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352135/
https://www.ncbi.nlm.nih.gov/pubmed/37308596
http://dx.doi.org/10.1038/s41594-023-01016-5

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