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Mito-TEMPO mitigates 5-fluorouracil-induced intestinal injury via attenuating mitochondrial oxidative stress, inflammation, and apoptosis: an in vivo study

BACKGROUND: Recent evidences highlight role of mitochondria in the development of 5-fluorouracil (5-FU)-induced intestinal toxicity. Mitochondria-targeted antioxidants are well-known for their protective effects in mitochondrial oxidative stress- mediated diseases. In the present study, we investiga...

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Detalles Bibliográficos
Autores principales: Tambe, Prasad Kisan, Qsee, H. S., Bharati, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352170/
https://www.ncbi.nlm.nih.gov/pubmed/37338659
http://dx.doi.org/10.1007/s10787-023-01261-6