Development and characterization of a fecal-induced peritonitis model of murine sepsis: results from a multi-laboratory study and iterative modification of experimental conditions

BACKGROUND: Preclinical sepsis models have been criticized for their inability to recapitulate human sepsis and suffer from methodological shortcomings that limit external validity and reproducibility. The National Preclinical Sepsis Platform (NPSP) is a consortium of basic science researchers, vete...

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Detalles Bibliográficos
Autores principales: Sharma, Neha, Chwastek, Damian, Dwivedi, Dhruva J., Schlechte, Jared, Yu, Ian-Ling, McDonald, Braedon, Arora, Jaskirat, Cani, Erblin, Eng, Mikaela, Engelberts, Doreen, Kuhar, Eva, Medeiros, Sarah K., Bourque, Stephane L., Cepinskas, Gediminas, Gill, Sean E., Jahandideh, Forough, Macala, Kimberly F., Panahi, Sareh, Pape, Cynthia, Sontag, David, Sunohara-Neilson, Janet, Fergusson, Dean A., Fox-Robichaud, Alison E., Liaw, Patricia C., Lalu, Manoj M., Mendelson, Asher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352196/
https://www.ncbi.nlm.nih.gov/pubmed/37460911
http://dx.doi.org/10.1186/s40635-023-00533-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352196/
https://www.ncbi.nlm.nih.gov/pubmed/37460911
http://dx.doi.org/10.1186/s40635-023-00533-3

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