Deep-profiling of phospholipidome via rapid orthogonal separations and isomer-resolved mass spectrometry

A lipidome comprises thousands of lipid species, many of which are isomers and isobars. Liquid chromatography-tandem mass spectrometry (LC-MS/MS), although widely used for lipidomic profiling, faces challenges in differentiating lipid isomers. Herein, we address this issue by leveraging the orthogon...

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Detalles Bibliográficos
Autores principales: Xia, Tian, Zhou, Feng, Zhang, Donghui, Jin, Xue, Shi, Hengxue, Yin, Hang, Gong, Yanqing, Xia, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352238/
https://www.ncbi.nlm.nih.gov/pubmed/37460558
http://dx.doi.org/10.1038/s41467-023-40046-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352238/
https://www.ncbi.nlm.nih.gov/pubmed/37460558
http://dx.doi.org/10.1038/s41467-023-40046-x

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