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Deep-profiling of phospholipidome via rapid orthogonal separations and isomer-resolved mass spectrometry
A lipidome comprises thousands of lipid species, many of which are isomers and isobars. Liquid chromatography-tandem mass spectrometry (LC-MS/MS), although widely used for lipidomic profiling, faces challenges in differentiating lipid isomers. Herein, we address this issue by leveraging the orthogon...
Autores principales: | Xia, Tian, Zhou, Feng, Zhang, Donghui, Jin, Xue, Shi, Hengxue, Yin, Hang, Gong, Yanqing, Xia, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352238/ https://www.ncbi.nlm.nih.gov/pubmed/37460558 http://dx.doi.org/10.1038/s41467-023-40046-x |
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