Cargando…

Structure and assembly of the NOT10:11 module of the CCR4-NOT complex

NOT1, NOT10, and NOT11 form a conserved module in the CCR4-NOT complex, critical for post-transcriptional regulation in eukaryotes, but how this module contributes to the functions of the CCR4-NOT remains poorly understood. Here, we present cryo-EM structures of human and chicken NOT1:NOT10:NOT11 te...

Descripción completa

Detalles Bibliográficos
Autores principales: Levdansky, Yevgen, Raisch, Tobias, Deme, Justin C., Pekovic, Filip, Elmlund, Hans, Lea, Susan M., Valkov, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352241/
https://www.ncbi.nlm.nih.gov/pubmed/37460791
http://dx.doi.org/10.1038/s42003-023-05122-4