Cargando…
Structure and assembly of the NOT10:11 module of the CCR4-NOT complex
NOT1, NOT10, and NOT11 form a conserved module in the CCR4-NOT complex, critical for post-transcriptional regulation in eukaryotes, but how this module contributes to the functions of the CCR4-NOT remains poorly understood. Here, we present cryo-EM structures of human and chicken NOT1:NOT10:NOT11 te...
Autores principales: | Levdansky, Yevgen, Raisch, Tobias, Deme, Justin C., Pekovic, Filip, Elmlund, Hans, Lea, Susan M., Valkov, Eugene |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352241/ https://www.ncbi.nlm.nih.gov/pubmed/37460791 http://dx.doi.org/10.1038/s42003-023-05122-4 |
Ejemplares similares
-
Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation
por: Raisch, Tobias, et al.
Publicado: (2019) -
Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos
por: Raisch, Tobias, et al.
Publicado: (2016) -
RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation
por: Poetz, Fabian, et al.
Publicado: (2021) -
Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome
por: Enwerem, Isioma I.I., et al.
Publicado: (2021) -
A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5′–3′ messenger RNA decay
por: Chang, Chung-Te, et al.
Publicado: (2019)