The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils

Neutrophils rely predominantly on glycolytic metabolism for their biological functions, including reactive oxygen species (ROS) production. Although pyruvate kinase M2 (PKM2) is a glycolytic enzyme known to be involved in metabolic reprogramming and gene transcription in many immune cell types, its...

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Detalles Bibliográficos
Autores principales: Toller-Kawahisa, Juliana Escher, Hiroki, Carlos Hiroji, Silva, Camila Meirelles de Souza, Nascimento, Daniele Carvalho, Públio, Gabriel Azevedo, Martins, Timna Varela, Damasceno, Luis Eduardo Alves, Veras, Flávio Protásio, Viacava, Paula Ramos, Sukesada, Fábio Yuji, Day, Emily Anne, Zotta, Alessia, Ryan, Tristram Alexander Jasper, Moreira da Silva, Rodrigo, Cunha, Thiago Mattar, Lopes, Norberto Peporine, Cunha, Fernando de Queiroz, O’Neill, Luke Anthony John, Alves-Filho, José Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352279/
https://www.ncbi.nlm.nih.gov/pubmed/37460614
http://dx.doi.org/10.1038/s41467-023-40021-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352279/
https://www.ncbi.nlm.nih.gov/pubmed/37460614
http://dx.doi.org/10.1038/s41467-023-40021-6

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