AraC interacts with p75(NTR) transmembrane domain to induce cell death of mature neurons

Cytosine arabinoside (AraC) is one of the main therapeutic treatments for several types of cancer, including acute myeloid leukaemia. However, after a high-dose AraC chemotherapy regime, patients develop severe neurotoxicity and cell death in the central nervous system leading to cerebellar ataxia,...

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Detalles Bibliográficos
Autores principales: Lopes-Rodrigues, Vanessa, Boxy, Pia, Sim, Eunice, Park, Dong Ik, Habeck, Michael, Carbonell, Josep, Andersson, Annika, Fernández-Suárez, Diana, Nissen, Poul, Nykjær, Anders, Kisiswa, Lilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352303/
https://www.ncbi.nlm.nih.gov/pubmed/37460457
http://dx.doi.org/10.1038/s41419-023-05979-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352303/
https://www.ncbi.nlm.nih.gov/pubmed/37460457
http://dx.doi.org/10.1038/s41419-023-05979-7

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