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Enabling programmable dynamic DNA chemistry using small-molecule DNA binders

The binding of small molecules to the double helical structure of DNA, through either intercalation or minor groove binding, may significantly alter the stability and functionality of DNA, which is a fundamental basis for many therapeutic and sensing applications. Here, we report that small-molecule...

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Detalles Bibliográficos
Autores principales: Xu, Junpeng, Wang, Guan Alex, Gao, Lu, Wu, Lang, Lei, Qian, Deng, Hui, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352304/
https://www.ncbi.nlm.nih.gov/pubmed/37460620
http://dx.doi.org/10.1038/s41467-023-40032-3