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Acquisition, co-option, and duplication of the rtx toxin system and the emergence of virulence in Kingella

The bacterial genus Kingella includes two pathogenic species, namely Kingella kingae and Kingella negevensis, as well as strictly commensal species. Both K. kingae and K. negevensis secrete a toxin called RtxA that is absent in the commensal species. Here we present a phylogenomic study of the genus...

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Detalles Bibliográficos
Autores principales: Morreale, Daniel P., Porsch, Eric A., Kern, Brad K., St. Geme, Joseph W., Planet, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352306/
https://www.ncbi.nlm.nih.gov/pubmed/37460464
http://dx.doi.org/10.1038/s41467-023-39939-8