Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma

Interplay between chromatin-associated complexes and modifications critically contribute to the partitioning of epigenome into stable and functionally distinct domains. Yet there is a lack of systematic identification of chromatin crosstalk mechanisms, limiting our understanding of the dynamic trans...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Li, Yinglu, Zhu, Fang, Xu, Xinjing, Estrella, Brian, Pazos, Manuel A., McGuire, John T., Karagiannis, Dimitris, Sahu, Varun, Mustafokulov, Mustafo, Scuoppo, Claudio, Sánchez-Rivera, Francisco J., Soto-Feliciano, Yadira M., Pasqualucci, Laura, Ciccia, Alberto, Amengual, Jennifer E., Lu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352330/
https://www.ncbi.nlm.nih.gov/pubmed/37460547
http://dx.doi.org/10.1038/s41467-023-39990-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352330/
https://www.ncbi.nlm.nih.gov/pubmed/37460547
http://dx.doi.org/10.1038/s41467-023-39990-5

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