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Inhibition of tyrosine kinase Fgr prevents radiation-induced pulmonary fibrosis (RIPF)

Cellular senescence is involved in the development of pulmonary fibrosis as well as in lung tissue repair and regeneration. Therefore, a strategy of removal of senescent cells by senolytic drugs may not produce the desired therapeutic result. Previously we reported that tyrosine kinase Fgr is upregu...

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Detalles Bibliográficos
Autores principales: Mukherjee, Amitava, Epperly, Michael W., Fisher, Renee, Hou, Wen, Shields, Donna, Saiful Huq, M., Pifer, Phillip M., Mulherkar, Ria, Wilhite, Tyler J., Wang, Hong, Wipf, Peter, Greenberger, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352363/
https://www.ncbi.nlm.nih.gov/pubmed/37460469
http://dx.doi.org/10.1038/s41420-023-01538-3