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Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma

Osteosarcoma (OS) is a common type of bone tumor for which there has been limited therapeutic progress over the past three decades. The prevalence of transcriptional addiction in cancer cells emphasizes the biological significance and clinical relevance of super-enhancers. In this study, we found th...

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Detalles Bibliográficos
Autores principales: Guo, Weitang, Wang, Xin, Lu, Bing, Yu, Jiaming, Xu, Mingxian, Huang, Renxuan, Cheng, Mingzhe, Yang, Meiling, Zhao, Wei, Zou, Changye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352384/
https://www.ncbi.nlm.nih.gov/pubmed/37460542
http://dx.doi.org/10.1038/s41419-023-05966-y