Dyrk1a Phosphorylation of α-Synuclein Mediating Apoptosis of Dopaminergic Neurons in Parkinson's Disease

OBJECTIVE: To investigate the role of aberrant Dyrk1a expression in phosphorylation modification at the α-synuclein serine 129 (Ser129) site to analyze its molecular mechanism in mediating apoptosis of PD. METHODS: The protein level of P-α-synuclein (Ser129), α-synuclein, Bcl-2, Bax, active caspase...

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Detalles Bibliográficos
Autores principales: Yong, Yuxuan, Wu, Qinfen, Meng, Xinling, Lu, Ranran, Xia, Huan, Pei, Feifei, Yang, Xinling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352525/
https://www.ncbi.nlm.nih.gov/pubmed/37469393
http://dx.doi.org/10.1155/2023/8848642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352525/
https://www.ncbi.nlm.nih.gov/pubmed/37469393
http://dx.doi.org/10.1155/2023/8848642

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