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Mid‐life leukocyte telomere length and dementia risk: An observational and mendelian randomization study of 435,046 UK Biobank participants

Telomere attrition is one of biological aging hallmarks and may be intervened to target multiple aging‐related diseases, including Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD). The objective of this study was to assess associations of leukocyte telomere length (T...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Xiang, Meiruo, Pilling, Luke C., Melzer, David, Wang, Lihong, Manning, Kevin J., Steffens, David C., Bowden, Jack, Fortinsky, Richard H., Kuchel, George A., Rhee, Taeho G., Diniz, Breno S., Kuo, Chia‐Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352557/
https://www.ncbi.nlm.nih.gov/pubmed/37254630
http://dx.doi.org/10.1111/acel.13808