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Clearance of senescent cells reverts the cigarette smoke‐induced lung senescence and airspace enlargement in p16‐3MR mice

Cigarette smoke (CS) leads to increased oxidative stress, inflammation, and exaggerated senescence, which are involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). While the role of cellular senescence in COPD is known, it is not clear if the removal of senescent cells could...

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Detalles Bibliográficos
Autores principales: Kaur, Gagandeep, Muthumalage, Thivanka, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352560/
https://www.ncbi.nlm.nih.gov/pubmed/37078230
http://dx.doi.org/10.1111/acel.13850