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Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain

Chemotherapy‐induced cognitive impairment (“chemobrain”) is a frequent side‐effect in cancer survivors treated with paclitaxel (PTX). The mechanisms responsible for PTX‐induced cognitive impairment remain obscure, and there are no effective treatments or prevention strategies. Here, we test the hypo...

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Detalles Bibliográficos
Autores principales: Ahire, Chetan, Nyul‐Toth, Adam, DelFavero, Jordan, Gulej, Rafal, Faakye, Janet A., Tarantini, Stefano, Kiss, Tamas, Kuan‐Celarier, Anna, Balasubramanian, Priya, Ungvari, Anna, Tarantini, Amber, Nagaraja, Raghavendra, Yan, Feng, Tang, Qinggong, Mukli, Peter, Csipo, Tamas, Yabluchanskiy, Andriy, Campisi, Judith, Ungvari, Zoltan, Csiszar, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352561/
https://www.ncbi.nlm.nih.gov/pubmed/37243381
http://dx.doi.org/10.1111/acel.13832