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Absent in melanoma 2 mediates aging‐related cognitive dysfunction by acting on complement‐dependent microglial phagocytosis

Pattern separation (PS) dysfunction is a type of cognitive impairment that presents early during the aging process, and this deficit has been attributed to structural and functional alterations in the dentate gyrus (DG) of the hippocampus. Absent in melanoma 2 (AIM2) is an essential component of the...

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Detalles Bibliográficos
Autores principales: Ye, Lei, Shu, Shu, Jia, Junqiu, Sun, Min, Xu, Siyi, Bao, Xinyu, Bian, Huijie, Liu, Yi, Zhang, Meijuan, Zhu, Xiaolei, Bai, Feng, Xu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352562/
https://www.ncbi.nlm.nih.gov/pubmed/37177836
http://dx.doi.org/10.1111/acel.13860