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Single‐cell landscape analysis reveals systematic senescence in mammalian Down syndrome

BACKGROUND: Down syndrome (DS), which is characterized by various malfunctions, is the most common chromosomal disorder. As the DS population continues to grow and most of those with DS live beyond puberty, early‐onset health problems have become apparent. However, the cellular landscape and molecul...

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Detalles Bibliográficos
Autores principales: Chen, Yao, Xiao, Yanyu, Zhang, Yanye, Wang, Renying, Wang, Feixia, Gao, Huajing, Liu, Yifeng, Zhang, Runju, Sun, Huiyu, Zhou, Ziming, Wang, Siwen, Chen, Kai, Sun, Yixi, Tu, Mixue, Li, Jingyi, Luo, Qiong, Wu, Yiqing, Zhu, Linling, Huang, Yun, Sun, Xiao, Guo, Guoji, Zhang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352595/
https://www.ncbi.nlm.nih.gov/pubmed/37461266
http://dx.doi.org/10.1002/ctm2.1310