CCNB1IP1 prevents ubiquitination‐mediated destabilization of MYCN and potentiates tumourigenesis of MYCN‐amplificated neuroblastoma

BACKGROUND: MYCN amplification as a common genetic alteration that correlates with a poor prognosis for neuroblastoma (NB) patients. However, given the challenge of directly targeting MYCN, indirect strategies to modulate MYCN by interfering with its cofactors are attractive in NB treatment. Althoug...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Yan, Hui, Zhou, Qiang, Wang, Penggao, Yang, Fang, Yuan, Ziqiao, Du, Qianming, Zhai, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352605/
https://www.ncbi.nlm.nih.gov/pubmed/37461251
http://dx.doi.org/10.1002/ctm2.1328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352605/
https://www.ncbi.nlm.nih.gov/pubmed/37461251
http://dx.doi.org/10.1002/ctm2.1328

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