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Impact of Nrf2 overexpression on cholangiocarcinoma treatment and clinical prognosis

PURPOSE: Nrf2 regulates antioxidant protein expression and protects against drug toxicity and oxidative stress, whereas Keap1 controls Nrf2 activity. The Keap1-Nrf2 pathway affects the prognosis of various cancers, however, its effect on cholangiocarcinoma chemoresistance and prognosis remains uncle...

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Detalles Bibliográficos
Autores principales: Lee, Huisong, Min, Seog Ki, Cho, Min-Sun, Lee, Hyeon Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Surgical Oncology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352705/
https://www.ncbi.nlm.nih.gov/pubmed/37449395
http://dx.doi.org/10.14216/kjco.23004