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Macrophage death in atherosclerosis: potential role in calcification

Cell death is an important aspect of atherosclerotic plaque development. Insufficient efferocytosis of death cells by phagocytic macrophages leads to the buildup of a necrotic core that impacts stability of the plaque. Furthermore, in the presence of calcium and phosphate, apoptotic bodies resulting...

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Detalles Bibliográficos
Autores principales: Neels, Jaap G., Gollentz, Claire, Chinetti, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352763/
https://www.ncbi.nlm.nih.gov/pubmed/37469518
http://dx.doi.org/10.3389/fimmu.2023.1215612