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Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells

Introduction: Engineered heart tissues (EHTs) are three-dimensional culture platforms with cardiomyocytes differentiated from human pluripotent stem cells (hPSCs) and were designed for assaying cardiac contractility. For drug development applications, EHTs must have a stable function and provide rep...

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Detalles Bibliográficos
Autores principales: Arefin, Ayesha, Mendoza, Melissa, Dame, Keri, Garcia, M. Iveth, Strauss, David G., Ribeiro, Alexandre J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352809/
https://www.ncbi.nlm.nih.gov/pubmed/37469866
http://dx.doi.org/10.3389/fphar.2023.1212092