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Exploiting inter-tissue stress signaling mechanisms to preserve organismal proteostasis during aging
Aging results in a decline of cellular proteostasis capacity which culminates in the accumulation of phototoxic material, causing the onset of age-related maladies and ultimately cell death. Mechanisms that regulate proteostasis such as cellular stress response pathways sense disturbances in the pro...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352849/ https://www.ncbi.nlm.nih.gov/pubmed/37469564 http://dx.doi.org/10.3389/fphys.2023.1228490 |