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Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition

BACKGROUND: Immediately after spinal trauma, immune cells, and proinflammatory cytokines infiltrate the spinal cord and disrupt the focal microenvironment, which impedes axon regeneration and functional recovery. Previous studies have reported that regulatory T cells (Tregs) enter the central nervou...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Li, Ying, Wang, Ziyue, Chen, Peng, Xie, Yi, Qu, Wensheng, Wang, Minghuan, Yu, Zhiyuan, Luo, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352886/
https://www.ncbi.nlm.nih.gov/pubmed/36914969
http://dx.doi.org/10.1111/cns.14161